Cancer Forums and News by PhD's


News | Forums Register

Go Back   Cancer Forums and News by PhD's > Cancer Forums and News

Cancer News

Breast
Colon
Kidney
Leukemia
Liver
Lung
Melanoma
Mesothelioma
Myeloma
Neck
Pancreatic
Prostate


Cancer Review

Breast
Colon
Kidney
Leukemia
Liver
Lung
Melanoma
Mesothelioma
Myeloma
Pancreatic
Prostate


 
Drop in breast cancer rates directly tied to reduced hormone therapy
By Dross at 2010-11-30 22:46
Drop in breast cancer rates directly tied to reduced hormone therapy

In a new UCSF study of more than 2 million mammogram screenings performed on nearly 700,000 women in the United States, scientists for the first time show a direct link between reduced hormone therapy and declines in ductal carcinomaterm in situ (DCIS) as well as invasive breast cancer. The researchers saw such a striking decrease, they believe they also have uncovered indirect evidence that hormones promote breast tumor growth.
The declines occurred in the age groups that most widely embraced then abandoned hormone therapy.

For nearly a decade, postmenopausal women have been strongly advised to refrain from long-term hormone therapy or to use the lowest dose possible for the shortest time to relieve hot flashes and night sweats. Numerous studies have suggested that women taking a combination of progestin and estrogen faced a higher risk of breast cancer and other potential health hazards.

The new findings suggest that hormones helped promote breast tumor growth of preexisting, clinically latent hormone-dependent cancers, not only increasing the incidents of invasive cancer, but also the risk of ductal carcinoma in situ (DCIS).

“We show that the incidence of breast cancer decreases if you take the hormones away,’’ said senior author Karla Kerlikowske, MD. “The fact that we’re continuing to see a decrease in invasive cancer means that the effects of stopping the hormones may be long-lasting.’’ 

The study has been published online by the “Journal of Clinical Oncology.’’ 
http://jco.ascopubs.org/content/early/2010/11/08/JCO.2010.29.5121.full.pdf+html?sid=b3f9dc48-1229-4ad7-877f-51e633bf1453



2221 reads

 
Search

sponsored links




Donate


Newsletter



Subscribe to our newsletter to receive info on our site or upcoming clinical trials
Email

Confirm your email address

HTML format
State

Please select the newsletters you want to sign up to:

  • Cancerfocus
    Receive updates from Cancerfocus.
  • Breast
  • Colon
  • Kidney
  • Leukemia
  • Liver
  • Lung
  • Melanoma
  • Mesothelioma
  • Myeloma
  • Neck
  • Pancreatic
  • Prostate





All times are GMT -5. The time now is 04:49 PM.