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Studying Cells in 3-D Could Reveal New Cancer Targets
By Dross at 2010-05-24 23:10
Showing movies in 3-D has produced a box-office bonanza in recent months. Could viewing cell behavior in three dimensions lead to important advances in cancer research? A new study led by Johns Hopkins University engineers indicates it may happen. Looking at cells in 3-D, the team members concluded, yields more accurate information that could help develop drugs to prevent cancer's spread.

The study, a collaboration with researchers at Washington University in St. Louis, appears in the June issue of Nature Cell Biology.

read more | 1509 reads

Heavy alcohol use, binge drinking, might increase risk of pancreatic cancer, researcher reports
By Dross at 2010-05-20 22:11

DALLAS – May 19, 2010 – Heavy alcohol use and binge drinking could increase the risk of pancreatic cancer in men, research from UT Southwestern Medical Center suggests.

In a study available online in Cancer Causes and Control, researchers found that the more alcohol a man consumed, the higher his risk of pancreatic cancer compared with those who drank little or no alcohol.

read more | 894 reads

Drug in new class of targeted therapies shows early promise against blood-related cancers
By Dross at 2010-05-20 22:10

HACKENSACK, N.J. (May 19, 2010) — A Phase I clinical trial of SNS-032, one of the first in a new class of drugs that inhibit cyclin-dependent kinases, demonstrated the drug's safety and potential clinical action against advanced chronic lymphocytic leukemiaterm (CLL). Cyclin-dependent kinases are enzymatic proteins that are integrally involved in cellular metabolism, renewal and signaling, and are thought to play key roles in the growth of cancers.

read more | 2386 reads

Impact of a chemoresponse assay on treatment costs for recurrent ovarian cancer
By gdpawel at 2010-04-30 00:06
Impact of a chemoresponse assay on treatment costs for recurrent ovarian cancer.
Havrilesky LJ, Krivak TC, Mucenski JW, Myers ER.
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Duke Comprehensive Cancer Center, Duke University Medical Center, Durham, NC.


We sought to estimate mean costs of chemotherapyterm treatment for recurrent ovarian cancer with or without use of a chemoresponse assay.

read more | 3 comments | 1301 reads

Experts call for further research into the relationship between insulin therapy and cancer
By Dross at 2010-03-10 00:18

The benefits of using insulin to treat diabetes far outweigh the risks, but a review just published online by IJCP, the International Journal of Clinical Practice, suggests that commonly used diabetes therapies may differ from each other when it comes to their influence on cancer risk.

Cancer expert Professor Michael Pollak from McGill University, Montreal, Canada, teamed up with diabetes expert Professor David Russell-Jones from The Royal Surrey County Hospital, Guildford, UK, to review more than three decades of laboratory and population studies.

read more | 1 comment | 1140 reads

Estrogen and Breast Tumor support
By Dross at 2010-03-10 00:17

MAYWOOD, Ill. -- A new study is providing insight into how estrogen fuels many breast cancers, and researchers say the findings could lead to new cancer-fighting drugs.


Researchers found that estrogen inhibits a protein called MLK3 that causes normal cell death. Blocking MLK3 leads to uncontrolled growth of cancer cells and resistance to chemotherapyterm.

Researchers from Loyola University Health System and three other centers reported the findings in the journal Cancer Research.

read more | 1984 reads

Plant derivative could help refine cancer treatment
By Dross at 2010-02-05 00:57

AUGUSTA, Ga. – Medical College of Georgia researchers are seeking to refine cancer treatment with an anti-inflammatory plant derivative long used in Chinese medicine.

Celastrol, derived from trees and shrubs called celastracaea, has been used for centuries in China to treat symptoms such as fever, chills, joint pain and inflammation. The MCG researchers think it may also play a role in cancer treatment by inactivating a protein required for cancer growth.

read more | 1006 reads

Promising results shown for kidney cancer drug
By Dross at 2010-02-05 00:55

The drug pazopanib (Votrient) slowed the progression of advanced renal cell carcinomaterm (RCC), a form of kidney cancer, in patients by 54% percent, according to a new study published in the Journal of Clinical Oncology.

read more | 7 comments | 1118 reads

Prolactin blocks oncogene associated with poor prognosis in breast cancer
By Dross at 2010-02-03 23:52

(PHILADELPHIA) Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive.

Publishing in the journal Cancer Research, the researchers discovered that prolactin, a pituitary hormone that normally stimulates breast development and milk production, in fact reduces levels of an oncogene called BCL6. The BCL6 protein has previously been shown to play a role in poorly differentiated breast cancer, which carries a poorer prognosis.

read more | 1518 reads

Blocking inflammation receptor kills breast cancer stem cells, U-M study finds
By Dross at 2010-01-07 02:55

ANN ARBOR, Mich. — Scientists at the University of Michigan Comprehensive Cancer Center have uncovered an important link between inflammation and breast cancer stem cells that suggests a new way to target cells that are resistant to current treatments.

read more | 1 comment | 1393 reads

Unraveling kidney cancer
By Dross at 2010-01-07 02:47

In a new study, scientists have searched for mutations in the gene regions of more than 100 kidney cancer samples, the largest number of samples from a single tumour type to be sequenced to date.

read more | 1 comment | 1619 reads

Anti-estrogens may offer protection against lung cancer mortality
By Dross at 2009-12-11 23:46

SAN ANTONIO – Anti-estrogens as therapy for breast cancer may also reduce the risk of death from lung cancer, according to study results presented at the CTRC-AACR San Antonio Breast Cancer Symposium, held here Dec. 9-13, 2009.

read more | 2 comments | 2327 reads

Tulane University Surgeon Pioneers 'Scarless' Thyroid Surgery
By Dross at 2009-11-25 22:53

Tulane University School of Medicine surgeon Dr. Emad Kandil is one of the first in the country to perform a new form of endoscopic surgery that uses a small incision under the arm to remove all or a portion of the thyroid or parathyroid glands without leaving a scar on the neck.

read more | 5 comments | 1085 reads

Laser therapy can aggravate skin cancer
By Dross at 2009-11-20 22:58

High irradiances of low-level laser therapy (LLLT) should not be used over melanomas. Researchers writing in the open access journal BMC Cancer studied the pain relieving, anti-inflammatory 'cold laser', finding that it caused increased tumour growth in a mouse model of skin cancer.

read more | 2109 reads

Rare pancreatic cancer patients may live longer when treated with radiation therapy
By Dross at 2009-11-20 22:57

Radiation therapy is effective in achieving local control and palliation in patients with pancreatic neuroendocrine tumors (PNTs), despite such tumors being commonly considered resistant to radiation therapy, according to a largest of its kind study in the November 15 issue of the International Journal of Radiation Oncology*Biology*Physics, the official journal of the American Society for Radiation Oncology (ASTRO).

read more | 1079 reads


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