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autologous
High-dose chemo and stem cell transplant shows little or no survival benefit for breast cancer
By Dross at 2007-12-14 00:24
 

High-dose chemotherapyterm and autologous stem cell transplantation, the controversial, arduous, yet once-popular combination treatment that fell out of favor as a therapy for breast cancer, has proven not to be beneficial as an adjuvant therapyterm for women with node-positive disease, according to an expansive analysis conducted by researchers at The University of Texas M. D. Anderson Cancer Center.

In a review of 15 randomized high-dose chemotherapy studies conducted around the world between 1988 and 2002, the investigators from M. D. Anderson, in collaboration with the European Blood and Marrow Transplant Group, report that while there was a slight benefit on relapse-free survival, there was no benefit to overall survival. Donald Berry, Ph.D., professor and head of the Division of Quantitative Sciences, presented the findings today at the 30th annual San Antonio Breast Cancer Symposium.

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